Publications by authors named "D I Feinstein"

Drug-induced lupus erythematosus (DILE) is an autoimmune reaction that results in symptoms of polyarthralgia, fever, and cutaneous lesions and other manifestations. Several drugs have been documented to cause this disease, including procainamide, isoniazid, methyldopa, penicillamine, and hydralazine. Systemic lupus erythematosus (SLE) manifestations often occur after the patient has been taking the drug without complications for months to years.

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  • Research highlights the significant role of immune processes in the development of Alzheimer's disease, which is the leading cause of dementia.
  • Various studies indicate that both innate and adaptive immune responses contribute to the disease's pathology and are influenced by genetics and lifestyle factors.
  • New therapeutic approaches targeting neuroinflammation are being explored in clinical settings, offering potential treatment options for Alzheimer's patients.
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  • * LAARs can cause severe bleeding (coagulopathy) in humans if blood levels exceed 10 ng/mL, leading to numerous poisonings each year.
  • * Various analytical methods, mainly using liquid chromatography-mass spectrometry (LC-MS), have been developed to quickly identify and analyze LAARs in patients experiencing severe bleeding, and these methods are evaluated for their validation and clinical utility.
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  • This literature review examines Sjogren's Syndrome (SS), a chronic autoimmune disorder that primarily affects the glands responsible for producing tears and saliva, leading to dryness in the eyes and mouth, as well as other serious health issues.
  • The study evaluates 15 research papers involving 1142 patients, focusing on various tear film biomarkers that could aid in diagnosing SS and distinguishing it from similar diseases.
  • Key findings highlight specific tear biomarkers, such as lysozyme and lactoferrin, which may have diagnostic potential and improve understanding of SS's impact on the body, paving the way for future research and treatment options.
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