Background: Suboptimal medication adherence is a major determinant of treatment outcome. Between a third and a half of prescribed medicines for long-term conditions are not taken as intended, the reasons for which are numerous and multifaceted. Improving medication adherence should optimise therapeutic outcomes.
View Article and Find Full Text PDFTonic-clonic seizures (TCSs), which present a significant risk for sudden unexpected death in epilepsy (SUDEP), require accurate detection to enable effective long-term monitoring. Previous studies have demonstrated the advantages of multimodal seizure detection systems in reliably detecting TCSs over extended periods. However, the effectiveness of these data-driven systems depends heavily on the availability of reliable training data.
View Article and Find Full Text PDFThe escalating global waste crisis necessitates innovative solutions. This study investigates the sustainable production of nanocellulose from biomass waste and its biomedical applications. Cellulose-rich materials-including wood, textiles, agricultural residues, and food by-products-were systematically processed using alkaline, acid, and oxidative pretreatments to enhance fiber accessibility.
View Article and Find Full Text PDFCommun Med (Lond)
February 2025
Background: Accurately recognizing that a person may be dying is central to improving their experience of care at the end-of-life. However, predicting dying is frequently inaccurate and often occurs only hours or a few days before death.
Methods: We performed urinary metabolomics analysis on patients with lung cancer to create a metabolite model to predict dying over the last 30 days of life.