Purpose: Cis-platinum and radiation in combination are current organ preservation treatment strategies for head and neck cancer. Their individual ototoxicity has been investigated, with recent demonstration of ototoxicity in clinical studies. Currently, no ototoxicity studies have been performed in animals receiving similar schedules of radiation or cis-platinum to those patients with head and neck cancer.
View Article and Find Full Text PDFArch Otolaryngol Head Neck Surg
February 2004
Objective: To estimate the prevalence of hypothyroidism in a population of patients with Ménière's disease (MD).
Design: Retrospective case-control study comparing the use of thyroid hormone supplements between patients with MD and controls.
Setting: Outpatient neurology clinic specializing in the management of patients experiencing dizziness.
A case is presented of a 43-year-old man with bilateral lesions of the inferior colliculus (IC) due to central nervous system lymphoma. Our patient was found to have relatively normal pure-tone averages with severely reduced bilateral word recognition scores. This case illustrates that the presentation of a partial bilateral IC lesion may be of severely reduced word recognition accompanied by nearly normal pure-tone hearing.
View Article and Find Full Text PDFObjective: To update the authors' experience with conservative management of acoustic neuromas.
Study Design: Retrospective chart review.
Setting: Private practice and tertiary care referral setting.
Otolaryngol Head Neck Surg
June 2001
Objective: This retrospective study focuses on 2 outcome results after surgical intervention for acoustic neuroma: (1) facial nerve status, and (2) hearing preservation.
Study Design: A total of 484 patients with an acoustic neuroma.
Results: Postoperative facial nerve outcomes were significantly different (P < 0.