Publications by authors named "D Heylen"
Proteomics stands as the crucial link between genomics and human diseases. Quantitative proteomics provides detailed insights into protein levels, enabling differentiation between distinct phenotypes. OLINK, a biotechnology company from Uppsala, Sweden, offers a targeted, affinity-based protein measurement method called Target 96, which has become prominent in the field of proteomics.
View Article and Find Full Text PDFBackground: Artificial intelligence (AI) tools hold much promise for mental health care by increasing the scalability and accessibility of care. However, current development and evaluation practices of AI tools limit their meaningfulness for health care contexts and therefore also the practical usefulness of such tools for professionals and clients alike.
Objective: The aim of this study is to demonstrate the evaluation of an AI monitoring tool that detects the need for more intensive care in a web-based grief intervention for older mourners who have lost their spouse, with the goal of moving toward meaningful evaluation of AI tools in e-mental health.
Xenodiagnosis in the wild: A methodology to investigate infectiousness for tick-borne bacteria in a songbird reservoir.
Curr Res Parasitol Vector Borne Dis
August 2024
A crucial factor to predict the persistence and spread of infections in natural systems is the capacity of reservoir hosts to maintain the infection and transmit it to others. This is known to greatly vary within and between species and through time, although the latter part of the variation is often less well understood in the wild. is one of the causal agents of Lyme disease in humans and is transmitted among avian hosts by the hard tick .
View Article and Find Full Text PDFArticle Synopsis
- The text discusses a study on genomic diversity in the great tit (Parus major), focusing on how environmental factors and demographic history impact genetic variation across different populations in Europe.
- The research, which is one of the most extensive genomic surveys for a wild vertebrate, involved analyzing about 500,000 SNP markers from 647 individuals across 29 populations to understand patterns of genomic divergence.
- Findings revealed that genetic differentiation varied significantly among populations, influenced by factors like local recombination rates and natural selection, with reduced diversity noted in island populations and evidence of recent adaptive changes at the edges of the species' range.
Article Synopsis
- Research indicates that vegetation and local host communities heavily influence the density and disease risk of Ixodes ricinus ticks in green spaces, yet micro-geographic variation remains less understood.
- The study measured various factors such as nymphal density, infection rates, and the presence of different pathogens in relation to recreational forest infrastructure using methods like vegetation surveys and tick pathogen screening.
- Results showed that tick density was highest in forest interiors, with lower disease risk near forest edges, and highlighted the importance of vegetation cover and local wildlife in influencing tick behavior and pathogen prevalence.