Reproducibility of liver ADC measurements using first moment optimized diffusion imaging.

Purpose: Cardiac-induced liver motion can bias liver ADC measurements and compromise reproducibility. The purpose of this work was to enable motion-robust DWI on multiple MR scanners and assess reproducibility of the resulting liver ADC measurements.

Methods: First moment-optimized diffusion imaging (MODI) was implemented on three MR scanners with various gradient performances and field strengths.

Hypoxaemic load in sleep apnoea is associated with acute changes in T-wave amplitude.

Aims: Obstructive sleep apnoea (OSA) imposes significant stress on the cardiovascular system and the heart. While long-term cardiac effects are understood, the immediate impact of hypoxaemia on the heart's electrophysiology lacks understanding. Our study aims to explore desaturation severity on cardiovascular repolarisation.

Prediction of MRI relaxometry in the presence of hepatic steatosis by Monte Carlo simulations.

To develop Monte Carlo simulations to predict the relationship of with liver fat content at 1.5 T and 3.0 T.

Multicenter, multivendor validation of liver quantitative susceptibility mapping in patients with iron overload at 1.5 T and 3 T.

Purpose: To evaluate the repeatability and reproducibility of QSM of the liver via single breath-hold chemical shift-encoded MRI at both 1.5 T and 3 T in a multicenter, multivendor study in subjects with iron overload.

Methods: This prospective study included four academic medical centers with three different MRI vendors at 1.

Reproducibility of intravoxel incoherent motion quantification in the liver across field strengths and gradient hardware.

Purpose: To evaluate reproducibility and interlobar agreement of intravoxel incoherent motion (IVIM) quantification in the liver across field strengths and MR scanners with different gradient hardware.

Methods: Cramer-Rao lower bound optimization was performed to determine optimized monopolar and motion-robust 2D (b-value and first-order motion moment [M]) IVIM-DWI acquisitions. Eleven healthy volunteers underwent diffusion MRI of the liver, where each optimized acquisition was obtained five times across three MRI scanners.