Publications by authors named "D Hemadri"
The bluetongue virus (BTV), transmitted by biting midges, poses a significant threat to livestock globally. This orbivirus induces bluetongue disease, leading to substantial economic losses in the agricultural sector. The current control measures have limitations, necessitating the development of novel, efficient vaccines.
View Article and Find Full Text PDFBacillus anthracis, a gram-positive bacillus capable of forming spores, causes anthrax in mammals, including humans, and is recognized as a potential biological weapon agent. The diagnosis of anthrax is challenging due to variable symptoms resulting from exposure and infection severity. Despite the availability of a licensed vaccines, their limited long-term efficacy underscores the inadequacy of current human anthrax vaccines, highlighting the urgent need for next-generation alternatives.
View Article and Find Full Text PDFComprehensive Spatial-Temporal and Risk Factor Insights for Optimizing Livestock Anthrax Vaccination Strategies in Karnataka, India.
Vaccines (Basel)
September 2024
Article Synopsis
- Anthrax is a zoonotic disease impacting livestock and humans, and the study aimed to identify environmental risk factors to create a better predictive risk map for vaccination.
- Researchers analyzed anthrax data from 2000-2023 in Karnataka, using machine learning to examine factors like temperature and soil quality to uncover spatial patterns and high-risk areas.
- The findings identified 11 high-risk districts with a basic reproduction number (Ro) greater than 1.50, suggesting targeted vaccination strategies, with herd immunity thresholds varying from 11.24% to 55.47%.
Article Synopsis
- Anthrax, caused by the bacterium Bacillus anthracis, is a significant zoonotic disease in livestock and humans, especially in Karnataka, India, necessitating a better understanding of its outbreaks.
- The study aims to analyze the relationship between anthrax outbreaks from 1987-2016 and climatic factors, using advanced statistical methods to develop predictive models for public health and vaccination strategies.
- Findings indicate that anthrax outbreaks are positively influenced by rainfall and wet days, with a long-term cycle of 6-8 years linked to Sea Surface Temperature anomalies, highlighting the importance of climate in prevention efforts.