The cervical wedge-shaped lesion in teeth: a light and electron microscopic study.

Background: The cervical non-carious wedged-shaped lesion is controversial in that its aetiology may involve attrition, erosion, abrasion and stress-corrosion (abfraction). This study examined the histopathology of anterior teeth with cervical wedge-shaped lesions by light and electron microscopy to elucidate their pathogenesis.

Methods: Ten undecalcified human teeth with cervical lesions were available for investigation.

Endodontic sequelae of dental erosion.

Background: The incidence of pulp involvement in patients with excessive wear has not been extensively documented.

Methods: Clinical records of 448 patients with excessive tooth wear were reviewed and 52 cases (11.6 per cent) with near or frank pulp exposures or root canal treatments were found and their numbers and sites were tabulated.

Ameloblast apoptosis and IGF-1 receptor expression in the continuously erupting rat incisor model.

Enamel-producing cells (ameloblasts) pass through several phenotypic and functional stages during enamel formation. In the transition between secretory and maturation stages, about one quarter of the ameloblasts suddenly undergo apoptosis. We have studied this phenomenon using the continuously erupting rat incisor model.

Dental erosion in asthma: a case-control study from south east Queensland.

Background: Asthma medication places patients at risk of dental erosion by reducing salivary protection against extrinsic or intrinsic acids. But patterns of lesions in asthmatics may differ from patterns in non-asthmatics, because gastro-oesophageal reflux (GOR) is found in 60 per cent of asthmatics.

Methods: The lesions in 44 asthma cases were compared to those of age and sex match controls with no history of asthma or medications drawn from the dental records of 423 patients referred concerning excessive tooth wear.

Th1 cytokines in oral lichen planus.

Background: Cell-mediated immune responses in oral lichen planus (OLP) may be regulated by cytokines and their receptors.

Methods: In situ cytokine expression and in vitro cytokine secretion in OLP were determined by immunohistochemistry and ELISA.

Results: The majority of subepithelial and intraepithelial mononuclear cells in OLP were CD8+.