A comparative study of secondary metabolites profiling and biological activity of L. leaf, flower and fruit.

Essential oil (EO) composition of was characterised by high proportion of furanosesquiterpenes (51.66-69.35%).

Clinical Features and Outcomes of Acute Kidney Injury in Critically Ill COVID-19 Patients: A Retrospective Observational Study.

Background: An alarming number of COVID-19 patients, especially in severe cases, have developed acute kidney injury (AKI).

Aim: The study aimed to assess the frequency, risk factors, and impact of AKI on mortality in critically ill COVID-19 patients.

Methods: The study was a retrospective observational study conducted in the MICU.

Reinforcing effect of tramadol in the rat.

Tramadol is one of the most commonly prescribed analgesic opioids in various pharmacopeias. Tramadol has been linked to abuse in recent clinical investigations. However, the behavioral effects and neural substrates of the drug have not been well characterized in preclinical studies.

Naltrexone promotes mechanical allodynia in humans and rats.

Mechanical allodynia has been studied in chronic naltrexone-treated people (N.T.P.