Mucoadhesion across scales: Towards the design of protein-based adhesives.

Mucoadhesion is a special case of bioadhesion in which a material adheres to soft mucosal tissues. This review elucidates our current understanding of mucoadhesion across length, time, and energy scales by focusing on relevant structural features of mucus. We highlight the importance of both covalent and non-covalent interactions that can be tailored to maximize mucoadhesive interactions, particularly concerning proteinaceous mucoadhesives, which have been explored only to a limited extent so far in the literature.

Exploiting cryo-EM structures of actomyosin-5a to reveal the physical properties of its lever.

Myosin 5a (Myo5a) is a dimeric processive motor protein that transports cellular cargos along filamentous actin (F-actin). Its long lever is responsible for its large power-stroke, step size, and load-bearing ability. Little is known about the levers' structure and physical properties, and how they contribute to walking mechanics.

Implementation of a mixed-methods heat acclimation programme in a professional soccer referee before the 2022 FIFA world cup in Qatar: a case study.

Objectives: This case study reports the real-world practicalities of implementing a mixed-methods heat acclimation (HA) programme before the 2022 FIFA World Cup.

Methods: One male English soccer referee (age: 44 years; height: 1.82 m; body mass: 76.

Identification and characterization of mycoviruses in transcriptomes from the fungal family ceratocystidaceae.

Mycoviruses pervade the fungal kingdom, yet their diversity within various fungal families and genera remains largely unexplored. In this study, 10 publicly available fungal transcriptomes from Ceratocystidaceae were analyzed for the presence of mycoviruses. Despite mycovirus associations being known in only four members of this family, our investigation unveiled the discovery of six novel mycoviruses.