Publications by authors named "D H LEVINTHAL"
Future Applications of Central Neuromodulation and Neurophysiological Testing in Cyclic Vomiting Syndrome.
Neurogastroenterol Motil
December 2024
Background: Cyclic vomiting syndrome (CVS) is defined by its episodic patterning. Furthermore, CVS is associated with other episodic disorders such as migraine and epilepsy. Indeed, many of the medications that are known to be useful for prophylaxis and abortive therapy in CVS are also effective in preventing and aborting migraines and seizures.
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- A study was conducted to understand the symptom patterns and natural history of cyclic vomiting syndrome (CVS) in adults over a 6-month period using daily electronic diaries.
- The research involved 93 enrolled patients, with 88 providing data; a significant number experienced CVS episodes, with a median of 0.6 episodes per month, lasting around 3 days on average.
- The findings indicate variability in episode patterns and emphasize the need for more precise definitions and characterizations of CVS episodes for better understanding and management of the condition.
Article Synopsis
- Cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS) involve sudden bouts of nausea, vomiting, and abdominal pain, significantly impacting patients' quality of life and often requiring emergency care.
- This paper reviews various treatment strategies for managing acute episodes of CVS and CHS, including both pharmacological options like triptans and antiemetics, as well as nonpharmacological methods like reducing stimuli and hot water baths.
- The authors emphasize the need for further research to create personalized treatment plans and advocate for compassionate emergency care for patients experiencing severe symptoms.
Description: The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update (CPU) is to review the available evidence and provide expert advice regarding the diagnosis and management of cyclic vomiting syndrome.
Methods: This CPU was commissioned and approved by the AGA Institute Clinical Practice Updates Committee (CPUC) and the AGA Governing Board to provide timely guidance on a topic of high clinical importance to the AGA membership, and underwent internal peer review by the CPUC and external peer review through standard procedures of Gastroenterology. This expert commentary incorporates important as well as recently published studies in this field, and it reflects the experiences of the authors who are experts in treating patients with cyclic vomiting syndrome.
Background: An increasing number of studies have explored the clinical features, epidemiology, pathophysiology, and management of cyclic vomiting syndrome (CVS). CVS is common in adults and children and negatively impacts patients, families, and the healthcare system. A related condition, cannabinoid hyperemesis syndrome (CHS), has been a focus of interest in the lay press and published literature.
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