Publications by authors named "D H K V Creytens"

Objectives: To evaluate the value of (dynamic) contrast-enhanced MRI for the diagnosis and follow-up of central cartilage tumors (CCT) of the proximal humerus, distal femur and proximal tibia.

Materials & Methods: 97 patients (44 ± 11 years, 31men) with a CCT (histopathologically proven and/or > 2 years follow-up (5 ± 3 years)) were retrospectively/consecutively included at the Ghent University Hospital (Belgium, 2003-2021). Thickness of the enhancing rim and dynamic contrast-enhanced MRI parameters of the entire tumor were calculated.

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Article Synopsis
  • The study investigates how glycan modifications on IgG antibodies affect their role in inflammation, focusing on patients with primary Sjögren disease (SjD).
  • Researchers analyzed IgG glycosylation in 300 patients, finding lower levels of sialylation and galactosylation in those with SjD compared to asymptomatic individuals; these changes correlate with increased B cell activation and various autoantibody profiles.
  • The findings suggest that IgG Fc glycosylation could serve as a new marker for predicting disease progression, monitoring activity, and assessing lymphoma risk in SjD patients.
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