Dopamine-mediated plasticity preserves excitatory connections to direct pathway striatal projection neurons and motor function in a mouse model of Parkinson's disease.

The cardinal symptoms of Parkinson's disease (PD) such as bradykinesia and akinesia are debilitating, and treatment options remain inadequate. The loss of nigrostriatal dopamine neurons in PD produces motor symptoms by shifting the balance of striatal output from the direct (go) to indirect (no-go) pathway in large part through changes in the excitatory connections and intrinsic excitabilities of the striatal projection neurons (SPNs). Here, we report using two different experimental models that a transient increase in striatal dopamine and enhanced D1 receptor activation, during 6-OHDA dopamine depletion, prevent the loss of mature spines and dendritic arbors on direct pathway projection neurons (dSPNs) and normal motor behavior for up to 5 months.

Mating Disruption of the California Red Scale, Aonidiella aurantii (Hemiptera: Diaspididae) in Central California Citrus.

A warmer climate and the development of pesticide resistance have led to an increase in the number of generations and higher population densities of California red scale, Aonidella aurantii (Maskell) in central California. Commercial citrus orchard studies were conducted to determine how effective mating disruption using CheckMate CRS was at reducing A. aurantii.

The Future of Organic Insect Pest Management: Be a Better Entomologist or Pay for Someone Who Is.

Insect pest management in certified organic production systems presents considerable challenges for growers. The Federal National Organic Program (NOP) guidelines list acceptable tactics, but their effective use requires a considerable knowledgebase in entomology. The range of tactics allowed by the NOP are viewed as limiting by many growers and there are important elements missing from the list such as pest monitoring and identification.

Temperature thresholds and degree-day model for Marmara gulosa (Lepidoptera: Gracillariidae).

The developmental thresholds for Marmara gulosa Guillén & Davis (Lepidoptera: Gracillariidae) were investigated in the laboratory by using 17, 21, 25, 29, and 33 degrees C. The lowest mortality occurred in cohorts exposed to 25 and 29 degrees C. Other temperatures caused >10% mortality primarily in egg and first and second instar sap-feeding larvae.