Publications by authors named "D H DEN BOER"
COVID-BLUeS - A Prospective Study on the Value of AI in Lung Ultrasound Analysis.
IEEE J Biomed Health Inform
February 2025
Unlabelled: As a lightweight and non-invasive imaging technique, lung ultrasound (LUS) has gained importance for assessing lung pathologies. The use of Artificial intelligence (AI) in medical decision support systems is promising due to the time- and expertise-intensive interpretation, however, due to the poor quality of existing data used for training AI models, their usability for real-world applications remains unclear.
Methods: In a prospective study, we analyze data from 63 COVID-19 suspects (33 positive) collected at Maastricht University Medical Centre.
The International Work Addiction Scale (IWAS): A screening tool for clinical and organizational applications validated in 85 cultures from six continents.
J Behav Addict
February 2025
Background And Aims: Despite the last decade's significant development in the scientific study of work addiction/workaholism, this area of research is still facing a fundamental challenge, namely the need for a valid and reliable measurement tool that shows cross-cultural invariance and, as such, allows for worldwide studies on this phenomenon.
Methods: An initial 16-item questionnaire, developed within an addiction framework, was administered alongside job stress, job satisfaction, and self-esteem measures in a total sample of 31,352 employees from six continents and 85 cultures (63.5% females, mean age of 39.
Objective: To describe the 12-month mortality of Dutch COVID-19 intensive care unit patients, the total COVID-19 population and various subgroups on the basis of the number of comorbidities, age, sex, mechanical ventilation, and vasoactive medication use.
Methods: We included all patients admitted with COVID-19 between March 1, 2020, and March 29, 2022, from the Dutch National Intensive Care (NICE) database. The crude 12-month mortality rate is presented via Kaplan-Meier survival curves for each patient subgroup.
Article Synopsis
- Gaucher disease (GD) is a genetic lysosomal storage disorder caused by a deficiency in the enzyme glucocerebrosidase (GBA1), and its diagnosis typically employs assays that can be compromised by background activity from other enzymes.
- Researchers have developed a selective fluorogenic substrate called 6-O-alkyl-4MU-β-Glc, which effectively targets GBA1 and avoids interference from other enzymes, making it suitable for diagnosing GD.
- Additionally, analyses of spleen samples from GD patients revealed increased levels of acylated and regular glycosyl lipids, highlighting a potential link between plant-derived glycosyl phytosterols and the disease, raising questions about their role in developing conditions like Parkinson's
Unlabelled: BackgroundThe Organisation for Economic Co-operation and Development (OECD) Patient-Reported Indicator Surveys (PaRIS) initiative aims to support countries in improving care for people living with chronic conditions by collecting information on how people experience the quality and performance of primary and (generalist) ambulatory care services. This paper presents the development of the conceptual framework that underpins the rationale for and the instrumentation of the PaRIS survey.
Methods: The guidance of an international expert taskforce and the OECD Health Care Quality Indicators framework (2015) provided initial specifications for the framework.