To excise or not: impact of MelaFind on German dermatologists' decisions to biopsy atypical lesions.

Objectives: To determine the biopsy sensitivity to melanoma of dermatologists in Germany and the impact of MelaFind® on their decisions to biopsy melanomas.

Design: Randomized two-armed online reader study presenting case information, clinical/dermatoscopic images of pigmented skin lesions and MelaFind results (Arm 2).

Methods: Each participant was asked to review 130 pigmented skin lesions.

Agreement of dermatopathologists in the evaluation of clinically difficult melanocytic lesions: how golden is the 'gold standard'?

Background: The 'gold standard' for the diagnosis of melanocytic lesions is dermatopathology. Although most of the diagnostic criteria are clearly defined, the interpretation of histopathology slides may be subject to interobserver variability.

Objectives: The aim of this study was to determine the variability among dermatopathologists in the interpretation of clinically difficult melanocytic lesions.

The performance of MelaFind: a prospective multicenter study.

Objective: To demonstrate the safety and effectiveness of MelaFind, a noninvasive and objective computer-vision system designed to aid in detection of early pigmented cutaneous melanoma.

Design: A prospective, multicenter, blinded study. The diagnostic performance of MelaFind and of study clinicians was evaluated using the histologic reference standard.

The diagnostic performance of expert dermoscopists vs a computer-vision system on small-diameter melanomas.

Objective: To evaluate the performance of dermoscopists in diagnosing small pigmented skin lesions (diameter
Design: Blinded comparison study.

Setting: Dermatologic hospital-based clinics and private practice offices.