Microarray Profiling of Vaccination-Induced Antibody Responses to SARS-CoV-2 Variants of Interest and Concern.

Mutations in surface proteins enable emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to escape a substantial fraction of neutralizing antibodies and may thus weaken vaccine-driven immunity. To compare available vaccines and justify revaccination, rapid evaluation of antibody (Ab) responses to currently circulating SARS-CoV-2 variants of interest (VOI) and concern (VOC) is needed. Here, we developed a multiplex protein microarray-based system for rapid profiling of anti-SARS-CoV-2 Ab levels in human sera.

Determinant factors of weight status among under two years children received the complementary feeding program.

Objective: The study explored determinant factors of weight status among children aged 12-24 months who received complementary feeding program of the Ministry of Health in Luwu Timur, South Sulawesi Province.

Methods: The study used case-control design. It involved 82 children from poor families who received complementary feeding program.

[SEPSIS IN SURGICAL PATIENT].

Epidemiological studies indicate a large incidence of sepsis in the general population. Despite advances in surgery, surgical patients with sepsis make almost one-third of all cases of sepsis. Sepsis is the leading cause of morbidity and mortality among surgical patients, with intra-abdominal infection as the main source of sepsis.

Effect of mycophenolate mofetil on progression of interstitial fibrosis and tubular atrophy after kidney transplantation: a retrospective study.

Objectives: Chronic transplant dysfunction after kidney transplantation is a major reason of kidney graft loss and is caused by immunological and non-immunological factors. There is evidence that mycophenolate mofetil (MMF) may exert a positive effect on renal damage in addition to immunosuppression, by its direct antifibrotic properties. The aim of our study was to retrospectively investigate the role of MMF doses on progression of chronic allograft dysfunction and fibrosis and tubular atrophy (IF/TA).