Publications by authors named "D Gulmez Sevim"
We investigate the impacts of a perinatal psychosocial intervention on trajectories of maternal mental health and child skills, from birth to age 3. We find improved maternal mental health and functioning (0.17 to 0.
View Article and Find Full Text PDFPurpose: Behçet's disease (BD) is an autoimmune chronic systemic inflammatory disease characterized by a versatile clinical spectrum. Growth arrest specific protein 6 (GAS6)/soluble AXL (sAXL) signaling pathway draws attention in the resolution of inflammation, and its deficiency is associated with chronic inflammatory, autoimmune diseases, as well as clearance of apoptotic cells by phagocytes - efferocytosis. In this study, it was aimed to investigate whether GAS6/sAXL, interleukin (IL)-10, nitric oxide (NO), and BCL-2 levels were associated with inflammation and efferocytosis contributes to the pathogenesis of BD.
View Article and Find Full Text PDFArticle Synopsis
- The study assessed the effectiveness and safety of adalimumab (ADA) in treating non-infectious uveitis (NIU) that isn't responsive to standard medications.
- A total of 24 patients, primarily with ocular Behçet syndrome, received varying doses of ADA and were evaluated for improvements in vision and inflammation at multiple time points over 24 weeks.
- Results showed significant improvements in visual acuity, inflammation metrics, and macular thickness without any serious side effects, indicating ADA's potential as a preferred treatment option for NIU in young patients.
We consider medical decision-making under diagnostic and therapeutic uncertainty and analyze how ambiguity aversion affects the decisions to test and treat, thereby contributing to the understanding of the observed heterogeneity of such decisions. We show that under diagnostic ambiguity (i.e.
View Article and Find Full Text PDFBackground: Coronavirus disease 2019 (Covid-19) has many different ocular manifestations. This study evaluates the effects of the disease and the steroid used in this disease on ocular structures.
Purpose: To evaluate the effects of Covid-19 and the steroids used in the treatment of severe infection on ocular structures and choroidal thickness.