Publications by authors named "D Groothof"
Article Synopsis
- Renal dysfunction is common in patients with Fontan circulation, with 12% showing renal issues based on eGFR measurements, and 24% based on cystatin C levels.
- Over an 11-year study, these patients experienced a faster decline in renal function compared to healthy individuals, averaging a drop of 1.36 ml/min/1.73 m/year.
- Higher levels of NT-proBNP at the start were linked to quicker drops in renal function, and worsened renal function over time was associated with increased mortality rates.
Purpose: Bone scintigraphy is key to non-invasively diagnosing wild-type transthyretin (ATTRwt) amyloidosis, and is mainly used to assess cardiac radiotracer uptake. However, extracardiac radiotracer uptake is also observed. We investigated whether intensity of soft tissue radiotracer uptake is associated with amyloid load in subcutaneous abdominal fat tissue and with mortality.
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