The K antigen is a major cause of hemolytic disease of the fetus and newborn (HDFN). K-HDFN is unique in that it can result in destruction of not just mature erythrocytes but fetal erythrocyte progenitors, causing severe fetal anemia earlier in pregnancy than other antigens. This poses a danger to fetal health as intrauterine transfusion (IUT), the preferred method of managing HDFN, becomes riskier earlier in pregnancy.
View Article and Find Full Text PDFThe causative agent of tuberculosis is still a widespread pathogen, which caused the death of ca. 1.6 million people globally in 2021.
View Article and Find Full Text PDFMyocardial injury occurs in 20% to 30% of hospitalized patients with COVID-19 infection, and cardiovascular complications contribute to approximately 40% of all COVID-19-related deaths. Most cases of myocarditis related to COVID-19 infection occur in the acute phase of infection and are self-limited. We describe a case of delayed-onset fulminant myocarditis that developed 5 weeks after mild COVID-19 infection leading to cardiogenic shock and the need for mechanical circulatory support.
View Article and Find Full Text PDFCutaneous leiomyosarcoma is a rare soft-tissue sarcoma that appears non-specific clinically and often is misdiagnosed as squamous cell carcinoma. We report the case of a 59-year-old Caucasian male with a grade I leiomyosarcoma tumor on his lower extremity with no previous history of local trauma. The tumor is composed of highly atypical spindle cells with pleomorphic nuclei and mitotic activity on hematoxylin and eosin stains.
View Article and Find Full Text PDFBackground: The incidence of 2 distinct tumor types occupying the same anatomic location is rarely observed and may be accounted for by 2 separate mechanisms: tumor-to-tumor metastasis and collision tumors, where 2 adjacent tumors invade one another. These rare phenomena arise from distinct mechanisms, which may affect their preoperative recognition, surgical approach, and postoperative care. We review 2 cases, highlighting their identification and perioperative management.
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