Publications by authors named "D Greig"
Diarrhoeagenic (DEC) pathotypes are defined by genes located on mobile genetic elements, and more than one definitive pathogenicity gene may be present in the same strain. In August 2022, UK Health Security Agency (UKHSA) surveillance systems detected an outbreak of hybrid Shiga toxin-producing /enterotoxigenic (STEC-ETEC) serotype O101:H33 harbouring both Shiga toxin () and heat-stable toxin (). These hybrid strains of DEC are a public health concern, as they are often associated with enhanced pathogenicity.
View Article and Find Full Text PDFIn July 2022, a genetically linked and geographically dispersed cluster of 12 cases of Shiga toxin-producing (STEC) O103:H2 was detected by the UK Health Security Agency using whole genome sequencing. Review of food history questionnaires identified cheese (particularly an unpasteurized brie-style cheese) and mixed salad leaves as potential vehicles. A case-control study was conducted to investigate exposure to these products.
View Article and Find Full Text PDFThe Chilean Society of Cardiology and Cardiovascular Surgery (SOCHICAR) is a scientific society whose mission is to improve the nation's cardiovascular health. Its primary goals include discussing issues affecting the specialty and engaging in various activities that support its advancement. To achieve these goals, numerous educational initiatives are undertaken for health professionals, including physicians in cardiology training programs.
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- * Researchers confirmed that the O1 isolates from these cases belonged to the seventh pandemic El Tor lineage (7PET) and identified virulence characteristics, antimicrobial resistance, and phylogenetic relationships among the strains.
- * The study found that 46 of 49 high-quality genomes belonged to the 7PET lineage, with a dominant subgroup likely contributing to the rise in cholera cases; it emphasized the need for whole genome sequencing in high-income countries to track the evolution of strains and antimicrobial resistance.
Article Synopsis
- One in four children with cerebral palsy (CP) will have orthopedic surgery, but effective pain management post-surgery is not well researched, which can lead to worse outcomes.
- This study aimed to assess the effectiveness of a multimodal surgical site injection combining ropivacaine, epinephrine, and ketorolac for pain control after hip dysplasia surgery in CP patients.
- A randomized, double-blind trial with 34 participants showed that those receiving the experimental injection needed significantly less narcotics than those who received a placebo, indicating better pain management.