Publications by authors named "D Gregg"

Article Synopsis
  • COVID-19 significantly affects coagulation in adult patients with congenital heart disease (ACHD), making them more susceptible to thromboembolic (TE) and bleeding complications.
  • In a study from May 2020 to November 2021 involving nearly 2,000 ACHD patients, 1.5% experienced severe TE or bleeding events, which were linked to higher mortality rates and more advanced health conditions.
  • Key risk factors for these complications included prior anticoagulation treatment, incidents of cardiac injury, and severity of the COVID-19 infection, with logistic regression confirming their independent associations with TE and bleeding risks.
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The bench-to-bedside development of pro-cognitive therapeutics for psychiatric disorders has been mired by translational failures. This is, in part, due to the absence of pharmacologically sensitive cognitive biomarkers common to humans and rodents. Here, we describe a cross-species translational marker of reward processing that is sensitive to the aminergic agonist, d-amphetamine.

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