Publications by authors named "D Grande"
Objective: To investigate management practices and outcomes in a retrospective cohort of patients who have sustained temporal bone gunshot wounds (TBGSW).
Study Design: Retrospective chart review.
Setting: Five participating hospitals.
Design of Collagen and Gelatin-based Electrospun Fibers for Biomedical Purposes: An Overview.
ACS Biomater Sci Eng
September 2024
Collagen and gelatin are essential natural biopolymers commonly utilized in biomaterials and tissue engineering because of their excellent physicochemical and biocompatibility properties. They can be used either in combination with other biomacromolecules or particles or even exclusively for the enhancement of bone regeneration or for the development of biomimetic scaffolds. Collagen or gelatin derivatives can be transformed into nanofibrous materials with porous micro- or nanostructures and superior mechanical properties and biocompatibility using electrospinning technology.
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- - Repairing DNA double strand breaks (DSBs) is essential for maintaining genome stability and cell survival, with key mechanisms including homologous recombination, non-homologous end joining, microhomology-mediated end joining, and single strand annealing.
- - The article introduces extrachromosomal reporter assays that selectively measure the effectiveness of each DSB repair pathway by evaluating the reconstitution of a nanoluciferase reporter gene in cells.
- - These assays are quick (under 24 hours), quantitative, sensitive, and suitable for high-throughput screening, making them valuable tools for DNA repair research and drug discovery.
Background: In recent years, organizational leaders have faced growing pressure to respond to social and political issues. Although previous research has examined the experiences of corporate CEOs engaging in these issues, less is known about the perspectives of healthcare leaders.
Objective: To explore the experiences of healthcare CEOs engaging in health-related social and political issues, with a specific focus on systemic racism and abortion policy.