Publications by authors named "D Graham Roblin"
Article Synopsis
- The study aimed to assess body measurement changes in patients with classic 46,XX congenital adrenal hyperplasia (CAH) and to evaluate how advances in diagnosis and treatment have influenced their growth over time.
- Researchers conducted a retrospective cohort study analyzing 76 CAH patients and 1,102 matched individuals under 21 years old, focusing on height, weight, and BMI percentiles.
- Findings indicated that CAH patients consistently scored lower in height percentiles compared to matched referents, with improvements noticeable following the implementation of new CAH guidelines, highlighting the need for further investigation into the mechanisms behind different growth patterns.
Context: The long-term effect of gender-affirming hormone therapy (GAHT) on glucose metabolism is an area of priority in transgender health research.
Objectives: To evaluate the relation between GAHT and changes in fasting blood glucose (FG) and glycosylated hemoglobin (HbA1c) in transmasculine (TM) and transfeminine (TF) persons relative to the corresponding temporal changes in presumably cisgender persons (ie, without any evidence of gender diversity).
Design: Retrospective cohort study.
Objective: The Centers for Disease Control and Prevention's 2022 Clinical Practice Guideline for Prescribing Opioids for Pain cautioned that inflexible opioid prescription duration limits may harm patients. Information about the relationship between initial opioid prescription duration and a subsequent refill could inform prescribing policies and practices to optimize patient outcomes. We assessed the association between initial opioid duration and an opioid refill prescription.
View Article and Find Full Text PDFBackground: In response to the opioid crisis in the United States, population-level prescribing of opioids has been decreasing; there are concerns, however, that dose reductions are related to potential adverse events.
Objective: Examine associations between opioid dose reductions and risk of 1-month potential adverse events (emergency department (ED) visits, opioid overdose, benzodiazepine prescription fill, all-cause mortality).
Design: This observational cohort study used electronic health record and claims data from eight United States health systems in a prescription opioid registry (Clinical Trials Network-0084).