Publications by authors named "D Giles"

Sport climbing requires a combination of physical and cognitive skills, with working memory (WM) playing a crucial role in performance. This study aimed to investigate the association between WM capacity and climbing ability, while considering potential confounding factors including sex, age, education level, and climbing experience. Additionally, the study compared prefrontal cortex (PFC) hemodynamic responses among different climbing ability groups and sex during WM performance.

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Understanding how the environment mediates an organism's ability to meet basic survival requirements is a fundamental goal of ecology. Vessel noise is a global threat to marine ecosystems and is increasing in intensity and spatiotemporal extent due to growth in shipping coupled with physical changes to ocean soundscapes from ocean warming and acidification. Odontocetes rely on biosonar to forage, yet determining the consequences of vessel noise on foraging has been limited by the challenges of observing underwater foraging outcomes and measuring noise levels received by individuals.

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Article Synopsis
  • * The research tested how leptin activates its receptors in the brain, specifically focusing on its impact on serotonergic neurons in the dorsal raphe nucleus (DRN) that communicate with the arcuate (ARC) region.
  • * Results showed that leptin decreases food intake in rats by acting through these serotonergic neurons, highlighting a new pathway that connects leptin and serotonin in regulating eating behavior, which could lead to better treatments for eating disorders.
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To understand the role of T cells in the pathogenesis of ulcerative colitis (UC), we analyzed colonic T cells isolated from patients with UC and controls. Here we identified colonic CD4 and CD8 T lymphocyte subsets with gene expression profiles resembling stem-like progenitors, previously reported in several mouse models of autoimmune disease. Stem-like T cells were increased in inflamed areas compared to non-inflamed regions from the same patients.

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The aerosol and precipitable water vapor (PW) distribution over the tropical Andes region is characterized using Aerosol Robotic Network (AERONET) observations at stations in Medellin (Colombia), Quito (Ecuador), Huancayo (Peru), and La Paz (Bolivia). AERONET aerosol optical depth (AOD) is interpreted using PM data when available. Columnar water vapor derived from ozone soundings at Quito is used to compare against AERONET PW.

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