Publications by authors named "D Ghaith"
Article Synopsis
- The study analyzed the impact of a bundled care approach on reducing device-associated infections (DAIs) in patients undergoing living donor liver transplantation (LDLT) over a three-year period.
- The implementation of the bundled care protocols led to significant reductions in rates of ventilator-associated pneumonia (VAP), catheter-associated urinary tract infections (CAUTI), and central line-associated bloodstream infections (CLABSI) through all study phases.
- Key pathogens identified in infections included Klebsiella pneumonia and Methicillin-resistant Staphylococcus aureus, emphasizing the importance of effective infection control practices post-transplant.
Introduction: The colonization of patients by carbapenemase-producing (CPE) has been associated with heightened mortality, especially in vulnerable individuals within intensive care units (ICUs). Our study aimed to comprehensively assess CPE prevalence among ICU patients across the Mediterranean region pre-COVID-19, conducting a multicenter prevalence study in the first quarter of 2019.
Methods: We collected clinical data and rectal or fecal samples from 256 ICU patients for CPE testing.
Background: Leptin (LEP) is an anti-obesity hormone that regulates food intake, energy expenditure, and glucose metabolism. The genetic variants in LEP and the LEP receptor (LEPR) gene may play an important role in the pathogenesis of type 2 diabetes mellitus (T2DM) and obesity. The current study aimed to investigate the association of serum LEP levels, and LEP polymorphisms in LEP (rs7799039, 2548 G/A) with T2DM in Egyptian patients.
View Article and Find Full Text PDFBackground: Immune paralysis can be defined as a hypoinflammatory state associated with the incapacity of the immune system to release proinflammatory mediators despite the clearance of pathogens by antimicrobials. Persistent immune paralysis leads to failure to eradicate primary infections with a substantial increase in the risk of multiorgan dysfunction and mortality. The state of immune paralysis is caused mainly by the diminished ability of monocytes to release proinflammatory cytokines in response to endotoxin.
View Article and Find Full Text PDF(1) Background: Type 2 diabetes mellitus (T2DM) and metabolic syndrome are associated with decreased vitamin D. In contrast, high pro-neurotensin (pro-NT) levels are linked with an increased risk of T2DM and cardiovascular disease. We aimed to determine the validity of pro-NT and 25-dihydroxy vitamin D3 levels as predictors for T2DM complications; (2) Methods: One hundred T2DM, and one hundred healthy volunteers participated in this case-control study.
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