Correlation between brain surface potassium and glucose utilization after bilateral cerebral ischemia in the gerbil.

The correlation between cerebral glucose utilization and brain surface potassium concentration (BS-K+) was studied during reperfusion following bilateral cerebral ischemia in the gerbil. Cerebral glucose utilization rate was measured by the 14C-2-deoxyglucose method and BS-K+ was continuously monitored by a potassium sensitive membrane electrode. BS-K+ increased from 3.

Multiprobe monitoring of ionic, metabolic, and electrical activities in the awake brain.

A new approach for studying brain metabolic, ionic, and electrical activities in the awake animal is described. We developed a multiprobe assembly holding electrodes for extracellular K+, pH, DC potential, electrocorticogram, and temperature as well as a light guide for monitoring intramitochondrial NADH oxidation-reduction state. The assembly was designed so that because of the type of electrodes used and the protection system around them, the same system could be used in many experiments.