Publications by authors named "D Gauvin"
This commentary discusses the implementation of fasting in nonclinical animal experimental subjects. The short-term removal of food from cages of experimental animals is in all respects innocuous. The term "stress" is ill-defined and the statutes and regulations governing animal research laboratories that exert their authority in the performance of their operations do so without substantive grounds to base compliance.
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- Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease that affects motor neurons, making it difficult to study its global impact due to variations in reporting and the disease's rapid progression.
- Researchers conducted a systematic review of existing studies published between 2010 and 2021, focusing on the incidence and prevalence of ALS worldwide, ultimately analyzing 140 articles for quality and data extraction.
- Results revealed significant disparities in ALS incidence (0.26 to 23.46 per 100,000 person-years) and prevalence (1.57 to 11.80 per 100,000), indicating gaps in disease reporting and the need for better epidemiological resources globally.
Introduction: Research on the health of older Veterans in Canada is an emerging area. Few population-based studies in Canada have included older Veterans as a specific group of interest. This paper describes a cohort of self-identified Veterans within the Canadian Longitudinal Study on Aging (CLSA).
View Article and Find Full Text PDFREL-1017 (esmethadone, D-methadone) is the opioid-inactive d-isomer of racemic D,L-methadone. REL-1017 may exert antidepressant effects via uncompetitive N-methyl-D-aspartate receptor (NMDAR) channel block. As REL-1017 is expected to exert central nervous system activity, full characterization of its abuse potential is warranted.
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