The optical, seismic, and infrasound signature of the March 5 2022, bolide over Central Italy.

On March 5, 2022, a 12 kg meteoroid crossed the sky above Central Italy and was observed by three different observational systems: the PRISMA all-sky camera network (10 stations), the Italian national seismic network (61 stations), and a 4-element infrasound array. The corresponding datasets, each with its own resolution, provided three independent assessments of the trajectory, size and speed of the meteoroid. The bolide traveled across central Italy with an azimuth of 102 degrees, becoming visible at about 91 km above sea level with a velocity of about 15.

The Zika virus infection remodels the expression of the synaptotagmin-9 secretory protein.

The exact mechanisms involved in flaviviruses virions' release and the specific secretion of viral proteins, such as the Non Structural protein-1 (NS1), are still unclear. While these processes might involve vesicular transport to the cell membrane, NS1 from some flaviviruses was shown to participate in viral assembly and release. Here, we assessed the effect of the Zika virus (ZIKV) NS1 expression on the cellular proteome to identify trafficking-related targets that may be altered in the presence of the viral protein.

Unravelling the epidemiological diversity of Zika virus by analyzing key protein variations.

The consequences of Zika virus (ZIKV) infections were limited to sporadic mild diseases until almost a decade ago, when epidemic outbreaks took place, with quick spread into the Americas. Simultaneously, novel severe neurological manifestations of ZIKV infections were identified, including congenital microcephaly. However, why the epidemic strains behave differently is not yet completely understood, and many questions remain about the actual significance of genetic variations in the epidemiology and biology of ZIKV.

Cosmogenic radionuclides in the Cavezzo meteorite: Gamma-ray measurement and detection efficiency simulations.

The Cavezzo meteorite was recovered on January 4, 2020, just three days after the fall observed over Northern Italy by the all-sky cameras of the Italian PRISMA fireball network. Two specimens, weighing 3.1 g (F1) and 52.

Novel effect of the high risk-HPV E7 CKII phospho-acceptor site on polarity protein expression.

Background: Oncogenic Human Papillomaviruses (HPVs) base their transforming potential on the action of both E6 and E7 viral oncoproteins, which perform cooperative or antagonistic actions and thus interfere with a variety of relevant cellular targets. Among them, the expression of some PDZ-containing polarity proteins, as DLG1 and hScrib, is altered during the HPV life cycle and the consequent malignant transformation. Together with the well-established interference of E6 with PDZ proteins, we have recently shown that E7 viral oncoprotein is also responsible for the changes in abundance and localization of DLG1 observed in HPV-associated lesions.