Publications by authors named "D Garcon"
Kinetic properties of gill (Na, K)-ATPase in the Pacific whiteleg shrimp Penaeus vannamei (Decapoda, Penaeidae).
Comp Biochem Physiol B Biochem Mol Biol
January 2025
Article Synopsis
- Penaeus vannamei is a rapidly growing shrimp species native to the Eastern Pacific, now found in tropical waters of Asia and the Americas, notable for its adaptability and disease resistance.
- Research focused on its osmoregulatory mechanisms highlights the role of the enzyme (Na, K)-ATPase, which is crucial for maintaining ionic balance, yet its modulation by different ligands is poorly understood.
- This study identifies important kinetic properties of the (Na, K)-ATPase in P. vannamei, revealing differences in enzyme behavior compared to other crustaceans, potentially aiding in understanding how these shrimp adapt to diverse salinity environments.
Primary amino acid sequences of decapod (Na, K)-ATPase provide evolutionary insights into osmoregulatory mechanisms.
Comp Biochem Physiol A Mol Integr Physiol
October 2024
Decapod Crustacea exhibit a marine origin, but many taxa have occupied environments ranging from brackish to fresh water and terrestrial habitats, overcoming their inherent osmotic challenges. Osmotic and ionic regulation is achieved by the gill epithelia, driven by two active ATP-hydrolyzing ion transporters, the basal (Na, K)-ATPase and the apical V(H)-ATPase. The kinetic characteristic of gill (Na, K)-ATPase and the mRNA expression of its α subunit have been widely studied in various decapod species under different salinity challenges.
View Article and Find Full Text PDFThe Macrobrachium amazonicum complex is composed of at least the Macrobrachium amazonicum and Macrobrachium pantanalense species, with the latter described from specimens originally identified as part of an endemic M. amazonicum population in the Brazilian Pantanal region. While there may be a reproductive barrier between these two Macrobrachium species, both are phylogenetically close, with small genetic distance.
View Article and Find Full Text PDFArticle Synopsis
- * Research indicates that mice lacking PCSK9 or treated with specific antibodies against PCSK9 show protection from gliadin-induced food allergies, evident by reduced intestinal symptoms and inflammation.
- * Notably, the protective effects of PCSK9 inhibition occur independently of the LDLR, as it remains effective even in LDLR-deficient mice, highlighting PCSK9's role in allergic responses.