Publications by authors named "D Galan-Madruga"

Article Synopsis
  • The study proposes a new laser-induced breakdown spectroscopy (LIBS) method for determining bioequivalence of generic drugs in vitro, focusing on the similarity between drug formulations rather than just dissolution performance.
  • This LIBS technique is efficient and straightforward, eliminating the need for complicated sample prep or expensive equipment, allowing direct application on drug samples.
  • The results showed that generic drugs tested were in vitro bioequivalent, meeting the regulatory standards of both American and European medicines agencies, even for drugs with very low active ingredients.
View Article and Find Full Text PDF

This article provides a detailed discussion of the evidence available to date on the application of laser-induced breakdown spectroscopy (LIBS) and supervised classification methods for the individual reassignment of commingled bone remains. Specialized bone chemistry studies have demonstrated the suitability of bone elemental composition as a distinct individual identifier. Given the widely documented ability of the LIBS technique to provide elemental emission spectra that are considered elemental fingerprints of the samples analyzed, the analytical potential of this technique has been assessed for the investigation of the contexts of commingled bone remains for their individual reassignment.

View Article and Find Full Text PDF

Scientific evidence sustains PM particles' inhalation may generate harmful impacts on human beings' health; therefore, their monitoring in ambient air is of paramount relevance in terms of public health. Due to the limited number of fixed stations within the air quality monitoring networks, development of methodological frameworks to model ambient air PM particles is primordial to providing additional information on PM exposure and its trends. In this sense, this work aims to offer a global easily-applicable tool to estimate ambient air PM as a function of meteorological conditions using a multivariate analysis.

View Article and Find Full Text PDF

Background: Regular monitoring of the air pollutant nitrogen dioxide (NO), an indicator for traffic-related emissions, is a priority in urban environments. The health impacts associated with NO exposure are the result of a combination of factors, including concentration, duration of exposure, and interactions with other pollutants. WHO has established air quality guidelines based on epidemiological studies.

View Article and Find Full Text PDF

The aim of this study is to assess and identify the most suitable geospatial interpolation algorithm for environmental sciences. The research focuses on evaluating six different interpolation methods using annual average PM concentrations as a reference dataset. The dataset includes measurements obtained from a target air quality network (scenery 1) and a sub-dataset derived from a partitive clustering technique (scenery 2).

View Article and Find Full Text PDF