Publications by authors named "D GIORGI"

Article Synopsis
  • Inappropriate therapies (ITs) in patients with implantable cardioverter-defibrillators (ICDs) are often triggered by supraventricular tachyarrhythmias (SVTs).
  • The THINGS study analyzed 526 patients with single-lead ICDs to estimate the IT incidence and identified factors like younger age and history of atrial fibrillation as significant risk contributors.
  • Results showed a low IT rate of 4.2% at one year and 7.1% at two years, with dual-chamber (DC) discrimination showing a trend towards fewer ITs compared to single-chamber (SC) discrimination in the VT zone.
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Background: Fibro-calcific aortic valve disease (FCAVD) is a progressive disorder characterized by the thickening and calcification of the aortic valve, eventually leading to aortic stenosis. Adiponectin and leptin, known for their anti-inflammatory and proinflammatory properties, respectively, have been implicated in cardiovascular diseases, but their associations with FCAVD are controversial. This meta-analysis aims to evaluate the relationships between adiponectin and leptin levels and FCAVD, particularly in patients with severe aortic stenosis (AS).

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Obesity is considered one of the main risk factors for cardiovascular diseases. The browning process has been recently recognized as a promising anti-obesity therapy. Lycopene (LYC) and fruit extract (GE) might be important resources for anti-obesity drugs; therefore, the aim of this study was to investigate the anti-obesity effects of LYC and GE on 3T3-L1 adipocytes and Zucker rats.

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Increased soil salinization, tightly related to global warming and drought and exacerbated by intensified irrigation supply, implies highly detrimental effects on staple food crops such as wheat. The situation is particularly alarming for durum wheat (DW), better adapted to arid/semi-arid environments yet more sensitive to salt stress than bread wheat (BW). To enhance DW salinity tolerance, we resorted to chromosomally engineered materials with introgressions from allied halophytic species.

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Background: Selective androgen receptor modulators (SARMs) are small synthetic drug molecules that are still not approved as medicine in Europe or the United States but are sold on illegal websites to improve sport performance, particularly bodybuilding.

Aim: To address the quality issues of illegal SARM products and their increasing diffusion in Italy with their potential health risks for consumers.

Methods: Web-based tools were used to investigate retail websites, trending searches, and information exchange via social media.

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