Occult COVID-19 in an immunosuppressed patient with migratory pulmonary infiltrates.

The clinical presentation of SARS-CoV-2 infection is often more severe and persistent in immunosuppressed hosts. We present the case of a patient with mantle cell lymphoma under treatment with rituximab and ibrutinib who had multiple hospitalizations with pulmonary infiltrates following mild SARS-CoV-2 infection and repeated negative nasopharyngeal (NP) RT-PCR tests. SARS-CoV-2 was eventually detected in bronchoalveolar lavage fluid and the symptoms resolved after treatment with remdesivir.

Early SARS-CoV-2 Reinfections Involving the Same or Different Genomic Lineages, Spain.

Centers for Disease Control and Prevention guidelines consider SARS-CoV-2 reinfection when sequential COVID-19 episodes occur >90 days apart. However, genomic diversity acquired over recent COVID-19 waves could mean previous infection provides insufficient cross-protection. We used genomic analysis to assess the percentage of early reinfections in a sample of 26 patients with 2 COVID-19 episodes separated by 20-45 days.

High-efficiency topological pumping with discrete supersymmetry transformations.

Making use of the isospectrality of Supersymmetry transformations, we propose a general and high-fidelity method to prepare gapped topological modes in discrete systems from a single-site excitation. The method consists of adiabatically connecting two superpartner structures, deforming the input state into the desired mode. We demonstrate the method by pumping topological states of the Su-Schrieffer-Heeger model in an optical waveguide array, where the adiabatic deformation is performed along the propagation direction.