Introduction: Gender-affirming hormone therapy (GAHT) is a cornerstone of gender-affirming care for transgender and gender diverse (TGD) patients, with a direct biological role on bone metabolism. However, a paucity of data describes how GAHT influences fracture rate over time. The study's primary objective was to describe the 5-year all-cause fracture incidence rate (IR) among TGD patients initiating estrogen-based GAHT (E-GAHT) or testosterone-based GAHT (T-GAHT), compared with TGD patients not using GAHT (non-GAHT).
View Article and Find Full Text PDFNeurosci Biobehav Rev
November 2024
Where do novel research questions come from? We suggest that identifying key computational problems and comparing solutions across domains can be one source. We exemplify this by looking at perception and action and outline how findings from one domain may generate novel research avenues in the other.
View Article and Find Full Text PDFThe nervous system utilizes prior information to enhance the accuracy of perception and action. Prevailing models of motor control emphasize Bayesian models, which suggest that the system adjusts the current motor plan by integrating information from previous observations. While Bayesian integration has been extensively examined, those studies usually applied a highly stable and predictable environment.
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