Benefits of a prolonged-release amino acid mixture in four pregnant women with phenylketonuria.

Maternal phenylketonuria (mPKU) is a pathologic condition occurring in the fetus of a mother with PKU that is caused by prolonged elevated intrauterine blood phenylalanine (Phe) levels, which can lead to congenital abnormalities and mental retardation of newborns. Management of PKU during pregnancy can be challenging as protein substitutes may exacerbate nausea, vomiting, and gastrointestinal symptoms. To report the successful management of four PKU pregnant women.

Symptoms of SARS-CoV-2 infection and vaccine status of sixty-seven adult patients affected by inherited metabolic diseases: a phone survey.

Background: The Covid pandemic seems to have had several detrimental effects on managing patients affected by inherited metabolic diseases (IMD), although published data about the impact of COVID-19 on patients suffering from IMD are very scarce. The scope of our work was to evaluate adherence to the vaccination plan, the side effects experienced by our adult IMD patients, and the symptoms of the SARS-CoV-2 infection.

Results: Sixty-seven patients agreed to respond to a phone interview.

Non-monotonic dose-response of di-(2-ethylhexyl) phthalate isolated from XT6 on adipogenesis and expression of and in 3T3-L1 adipocytes.

Objectives: Adipogenesis is the fat cell formation process regulated by peroxisome proliferator-activated receptors (). The insulin-responsive glucose transporter 4 () has a major role in glucose uptake and metabolism in insulin target tissues (i.e.

Self-Medication Profile of Adult Patients with Temporomandibular Disorders in Southeast Brazil.

Background: Patients with temporomandibular disorder (TMD) often have orofacial pain and may use medication without professional prescription. Self-medication and inappropriate drug intake may cause serious health problems. This cross-sectional study evaluated the self-medication profile of TMD patients, the most used medications and their effect, and the relation between self-medication and socioeconomic factors.

Probiotics alter biofilm formation and the transcription of virulence-associated genes.

Background And Objective: The potential of probiotics on the prevention and control of periodontitis and other chronic inflammatory conditions has been suggested. and species influence interaction with gingival epithelial cells (GECs) but may not act in a unique way. In order to select the most appropriate probiotic against , we aimed to evaluate the effect of several strains on biofilm formation and transcription virulence-associated factors (PgVAFs).