Collective motion of energy depot active disks.

In the present work we have studied collectives of active disks with an energy depot, moving in the two-dimensional plane and interacting an excluded volume. The energy depot accounts for the extraction of energy taking place at the level of each particle in order to perform self-propulsion, included in an underdamped Langevin dynamics. We show that this model undergoes a flocking transition, exhibiting some of the key features of the Vicsek model, namely, band formation and giant number fluctuations.

Noise-Induced Phase Separation and Time Reversal Symmetry Breaking in Active Field Theories Driven by Persistent Noise.

Within the Landau-Ginzburg picture of phase transitions, scalar field theories develop phase separation because of a spontaneous symmetry-breaking mechanism. This picture works in thermodynamics but also in the dynamics of phase separation. Here we show that scalar nonequilibrium field theories undergo phase separation just because of nonequilibrium fluctuations driven by a persistent noise.

Fermented Wheat Germ Protein with Histone Deacetylase Inhibitor AR42 Demonstrates Enhanced Cytotoxicity against Lymphoma Cells In Vitro and In Vivo.

Current treatments for lymphoma are plagued by substantial toxicity and the inability to overcome drug resistance, leading to eventual relapse and rationalizing the development of novel, less toxic therapeutics and drug combinations. Histone deacetylase inhibitors (HDACis) are a broad class of epigenetic modulators that have been studied in multiple tumor types, including lymphoma. Currently, HDACis are FDA-approved for treating relapsed T-cell lymphomas and multiple myeloma, with ongoing trials in other lymphomas and solid tumors.

Phase Coexistence and Edge Currents in the Chiral Lennard-Jones Fluid.

We study a model chiral fluid in two dimensions composed of Brownian disks interacting via a Lennard-Jones potential and a nonconservative transverse force, mimicking colloids spinning at a given rate. The system exhibits a phase separation between a chiral liquid and a dilute gas phase that can be characterized using a thermodynamic framework. We compute the equations of state and show that the surface tension controls interface corrections to the coexisting pressure predicted from the equal-area construction.

Fluid-Glass-Jamming Rheology of Soft Active Brownian Particles.

We numerically study the shear rheology of a binary mixture of soft active Brownian particles, from the fluid to the disordered solid regime. At low shear rates, we find a Newtonian regime, where a Green-Kubo relation with an effective temperature provides the linear viscosity. It is followed by a shear-thinning regime at high shear rates.