Association between lesion depth and placement technique with failures requiring extraction of preformed metal crowns in primary molars. A retrospective study.

Purpose: The aim of the present study was to evaluate the factors associated with failure requiring extraction after placement of preformed metal crowns (PMCs) in primary molars. Radiographic caries depth at baseline (initial/moderate and severe) and placement technique (Conventional and Hall technique) and other patient-related variables were analysed.

Methods: Clinical and radiographic records from children aged 2-10 years who had at least one primary molar treated with PMCs between 2011 and 2019 were evaluated.

Do Symptoms of Depression Moderate the Links Between Reactive and Proactive Aggression and Frequency of Substance Use?

Youth substance use continues to be a public health concern, with both aggressive behavior and symptoms of depression commonly identified as risk factors for adolescent substance use. However, more research is needed to understand how proactive and reactive functions of aggression are uniquely associated with the frequency of use of specific substances and how these functions of aggression interact with symptoms of depression to contribute to substance use. To this end, the current study examined these associations in a sample of detained youth (N = 229; 80.

Evaluating Treatment Patterns and the Role of Neoadjuvant Chemotherapy in Plasmacytoid Urothelial Carcinoma: Insights from a Combined National and Institutional Series.

Background: Plasmacytoid urothelial carcinoma (PUC) is a rare histologic subtype of urothelial carcinoma of the bladder (BC). Our objective was to characterize treatment patterns and outcomes of PUC in the NCDB and our recent institutional experience.

Methods: The NCDB was queried for localized PUC cases between 2004 and 2020.

assessment of the immunomodulatory effects of probiotic strains on chicken PBMCs.

The beneficial effects of feeding probiotic DSM 32315 (BS) and CECT 5940 (BV) to chickens are well-documented, with potential immune modulation as a key mechanism. In this study, we investigated the direct interactions of chicken peripheral blood mononuclear cells (PBMCs) with BS or BV through whole transcriptome profiling and cytokine array analysis. Transcriptome profiling revealed 20 significantly differentially expressed genes (DEGs) in response to both treatments, with twelve DEGs identified in BS-treated PBMCs and eight in BV-treated PBMCs.