Publications by authors named "D G Deutsch"

Article Synopsis
  • Researchers have created a detailed neuronal wiring diagram of the whole brain of a fruit fly (Drosophila melanogaster), mapping over 5 billion chemical synapses between more than 139,000 neurons, to better understand brain function.
  • The study includes detailed annotations about various cell types, nerve pathways, and neurotransmitter identities, and the data is freely available for other researchers to use and explore.
  • By analyzing synaptic pathways and connections, the project helps illustrate how neural structures relate to sensorimotor behaviors, paving the way for similar studies in other species.
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Article Synopsis
  • - The study investigated how self-perceived constipation severity (CS) affects colonic response to eating in patients with different constipation phenotypes, involving 387 outpatients diagnosed with chronic idiopathic constipation.
  • - Key findings revealed that female patients experienced higher bloating and lower stool quality, while CS levels were correlated with bloating and colonic transit times in both irritable bowel syndrome with constipation (IBS-C) and functional constipation (FC).
  • - Interestingly, while colonic transit response to eating (CTRE) was linked to CS in FC and defecation disorder (DD) patients, it didn't show the same association in IBS-C patients, suggesting differing mechanisms at play.
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Infantile hypertrophic pyloric stenosis is a common surgical disease in infants, with an incidence of 2 to 5 cases per 1000 live births. It often presents with nonbilious projectile vomiting after feeding and a mid-epigastric mass in infants between the third and eighth weeks of life. Ramstedt pyloromyotomy remains the gold standard of treatment.

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Aims: Cartilage injuries rarely heal spontaneously and often require surgical intervention, leading to the formation of biomechanically inferior fibrous tissue. This study aimed to evaluate the possible effect of amelogenin on the healing process of a large osteochondral injury (OCI) in a rat model.

Methods: A reproducible large OCI was created in the right leg femoral trochlea of 93 rats.

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