Publications by authors named "D G Chapple"

The human-mediated transportation of stowaway individuals to non-native regions is a major driver of new biological invasions, and the post-establishment spread of the invader in its introduced range. In order for the stowaway individuals to successfully establish in the non-native region, they must survive the harsh conditions during the journey (e.g.

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The subspecies rank has been widely applied by taxonomists to capture infraspecific variation within the Linnaean classification system. Many subspecies described throughout the 20th century were recognised largely based on perceived variation in single morphological characters yet have since been found not to correspond to separately evolving population lineages, thus requiring synonymy or elevation to full species under lineage-based views of species. These modern lineage-based taxonomic resolutions have resulted from a combination of new molecular genetic techniques, improved geographical sampling of specimens, and more sophisticated analyses of morphological variation (e.

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A species of diurnal skink from the Hawkdun, Ida, and Saint Bathans Ranges of North Otago, Aotearoa/New Zealand is described as Oligosoma eludens sp. nov. It is a small species, coloured mid- to dark brown with especially fine, smooth longitudinal stripes, and lives along the edges of greywacke screes in alpine grasslands.

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A new species of rock skink Liopholis Fitzinger 1843 (Scincidae) is described from the Mann-Musgrave Ranges of north-western South Australia. Liopholis margaretae sensu lato (Storr 1968) is currently known to occur in two disjunct populations: the MacDonnell Ranges bioregion and nearby regions in the Northern Territory, and the Central Ranges bioregion in South Australia. Based on morphological examination of both museum and field specimens, as well as on newly generated molecular data, we show that specimens from these two ranges constitute distinct species.

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The gastrin-releasing peptide receptor (GRPR) is overexpressed in a variety of cancers and represents a promising target for diagnosis and therapy. However, the extremely high accumulation in the pancreas observed for most of the clinically evaluated GRPR-targeted radiopharmaceuticals could limit their applications. In this study, we synthesized one GRPR antagonist (ProBOMB5) and two GRPR agonists (LW02056 and LW02057) by replacing the 4-thiazolidinecarboxylic acid (Thz) residue in our previously reported GRPR-targeted tracers with Pro.

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