Publications by authors named "D G Brodland"
Article Synopsis
- The study analyzes the use of large language models (LLMs) as educational tools for patients considering Mohs micrographic surgery (MMS), focusing on their effectiveness and accuracy.* -
- A panel of 15 MMS surgeons assessed LLM-generated responses to common patient questions, finding that most responses were appropriate and 75% rated as mostly accurate, with ChatGPT scoring the highest in accuracy.* -
- While LLM responses were deemed appropriate, only 33% were considered sufficient for clinical use, and their complexity may hinder patient understanding, highlighting the need for dermatologists to recognize these limitations.*
Background: The surgical management of leg wounds following skin cancer extirpation is challenging. Pinch grafting (PG) is a technique that has been rarely described in the reconstruction of acute surgical wounds.
Objective: The purpose of this study was to evaluate whether PG resulted in faster healing times for below the knee wounds following Mohs micrographic surgery (MMS) when compared with second intention healing (SIH).
Background: Mohs surgery for melanoma has been performed for many decades, but advances in the use of immunohistochemistry with frozen sections during Mohs surgery have allowed for more accurate, reliable, and efficient margin assessment with improved local control of the disease.
Objective: To describe the use of MART-1 in treating melanoma with Mohs surgery and serve as a primer for the Mohs surgeon adding melanoma cases to their repertoire.
Materials And Methods: Review of the literature and discussion of experience with Mohs for melanoma.
Integrating the 40-Gene Expression Profile (40-GEP) Test Improves Metastatic Risk-Stratification Within Clinically Relevant Subgroups of High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) Patients.
Dermatol Ther (Heidelb)
March 2024
Introduction: The validated 40-gene expression profile (40-GEP) test independently stratifies risk of regional or distant metastasis for cutaneous squamous cell carcinoma (cSCC) tumors with high-risk clinicopathologic features. This study evaluated the stratification of risk by the 40-GEP test in a large cohort of tumors with one or more high-risk factors and in clinically relevant subgroups, including tumors within National Comprehensive Cancer Network (NCCN) high- and very-high-risk groups, lower-stage BWH T1 and T2a tumors, and patients > 65 years old.
Methods: This multicenter (n = 58) performance study of the 40-GEP included 897 patients.