The sensitive orthophenanthroline test was used to reveal paracoagulation in 27 normal newborns, thrombinemia reaching the highest level at the moment of birth and in the period of heavy depression of blood coagulation (on the fifth day of life) was detected. It has been suggested that the physiological role of thrombinemia is in the leveling of hypocoagulation shifts and providing of the local hemostasis. To escape thrombotic complications, drug correction of the hypocoagulation physiological level (activity of prothrombin complex factors is 30-60%) is not recommended.
View Article and Find Full Text PDF