Publications by authors named "D G Bakalova"
Psychological Predictors of COVID-19-Related Anxiety in Vulnerable Groups.
Eur J Investig Health Psychol Educ
September 2023
Article Synopsis
- The study investigates factors that contribute to COVID-19-related anxiety, focusing on vulnerable groups like working parents and individuals with chronic conditions.
- Psychological factors such as stress and anxiety were found to be weak positive predictors of COVID-19 anxiety in vulnerable groups, but had a stronger impact on those with multiple vulnerabilities.
- The research highlights the need for targeted interventions that address both the psychological challenges of vulnerable populations and the positive traits in non-vulnerable groups, advocating for a more nuanced approach to mental health during crises.
Study Question: Can chromosomal abnormalities beyond copy-number aneuploidies (i.e. ploidy level and microdeletions (MDs)) be detected using a preimplantation genetic testing (PGT) platform?
Summary Answer: The proposed integrated approach accurately assesses ploidy level and the most common pathogenic microdeletions causative of genomic disorders, expanding the clinical utility of PGT.
Detection of chromosomal aneuploidies and monogenic disorders in preimplantation embryos is essential for selecting the best embryo for transfer during in vitro fertilization to achieve a healthy pregnancy. Preimplantation genetic testing (PGT) is typically performed on preimplantation embryos to select a genetically normal embryo for transfer. A trophectoderm biopsy is necessary for PGT; this is an invasive procedure to the embryo that requires specialized equipment and highly trained embryologists, resulting in high costs associated with in vitro fertilization treatment.
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