Publications by authors named "D G Achel"

Tubaani is a local delicacy prepared with leaves. The leaves may contain trace/heavy metals and important phytonutrients that could impact consumers' health. Concerns over the nutritional and toxicological implications of leaves are critical.

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Carnosic acid (CA) is a phenolic diterpene characterized by its high antioxidant activity; it is used in industrial, cosmetic, and nutritional applications. We evaluated the radioprotective capacity of CA on cells directly exposed to X-rays and non-irradiated cells that received signals from X-ray treated cells (radiation induced bystander effect, RIBE). The genoprotective capacity was studied by in vivo and in vitro micronucleus assays.

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Introduction: to address the challenge of inadequate and non-equitable distribution of diagnostic imaging equipment, countries are encouraged to evaluate the distribution of installed systems and undertake adequate monitoring to ensure equitability. Ghana´s medical imaging resources have been analyzed in this study and evaluated against the status in other countries.

Methods: data on registered medical imaging equipment were retrieved from the database of the Nuclear Regulatory Authority and analyzed.

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Article Synopsis
  • Whole-brain radiation therapy (WBRT) and stereotactic radiosurgery (SRS) are key treatments for brain metastases, with this study focusing on the effectiveness of volumetric modulated arc therapy (VMAT-RS) in breast cancer patients.
  • 18 breast cancer patients with 41 brain metastases were evaluated, revealing that HER2+ patients had significantly longer median survival times, with the cerebellum being the most common location for metastases.
  • The findings indicate that VMAT-RS offers comparable survival rates to other radiosurgery methods, highlighting that patients' baseline conditions and cancer subtypes play a crucial role in influencing outcomes.
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Flavonoids constitute a group of polyphenolic compounds characterized by a common gamma-benzo- pyrone structure considered in numerous biological systems to possess antioxidant capacity. Among the different applications of flavonoids, its genoprotective capacity against damage induced by ionizing radiation stands out, which has been related to antioxidant activity and its chemical structure. In this study, we determined the frequency of appearance of micronucleus in vivo by means of the micronucleus assay.

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