Fiber optics passive monitoring of groundwater temperature reveals three-dimensional structures in heterogeneous aquifers.

Alluvial aquifers often exhibit highly conductive embedded formations that can act as preferential pathways for the transport of solutes. In this context, a detailed subsurface characterization becomes crucial for an effective monitoring of groundwater quality and early detection of contaminants. However, small-scale heterogeneities are seldom detected by traditional nondestructive investigations.

Ketosis-prone Diabetes Presenting with Acute Esophageal Necrosis or "Black Esophagus": An Intriguing New Clinical Association.

Background: Ketosis-prone diabetes (KPD) is an intermediate subtype of diabetes mellitus, usually affecting Afro-American adults, presenting with diabetic ketoacidosis (DKA), without the classic phenotype of autoimmune type 1 diabetes. Patients require insulin therapy at onset for the acute decompensation, then usually remain insulin-free for prolonged periods with diet alone or with other antidiabetic drugs. DKA can be rarely complicated by upper gastrointestinal bleeding and mucosal necrosis, a severe complication named acute esophageal necrosis (AEN) burdened by high mortality.

Urate Crystals; Beyond Joints.

Gout is the most common inflammatory arthropathy caused by the deposition of monosodium urate (MSU) crystals. The burden of gout is substantial with increasing prevalence of gout globally. The prevalence of Gout in the United States has increased by over 7% in the last two decades.

Preliminary dosimetric analysis of DOTA-folate radiopharmaceutical radiolabelled with Sc produced through V(p,x)Sc cyclotron irradiation.

Sc is one of the most promising theranostic radionuclides, thanks to its low energy γ-ray emission (159 keV), suitable for single photon emission computed tomography imaging and its intense β emission, useful for tumour treatment. Despite promising preclinical results, the translation of Sc-therapeutic agents to the clinic is hampered by its limited availability. Among different Sc-production routes currently being investigated, the V(p,x)Sc reaction has proved to be of particular interest, thanks to the low-cost and easy availability on the market of V material and the diffusion of medium energy proton cyclotrons.