Publications by authors named "D Frieske"

ARCIMBOLDO solves the phase problem at resolutions of around 2 Å or better through massive combination of small fragments and density modification. For complex structures, this imposes a need for a powerful grid where calculations can be distributed, but for structures with up to 200 amino acids in the asymmetric unit a single workstation may suffice. The use and performance of the single-workstation implementation, ARCIMBOLDO_LITE, on a pool of test structures with 40-120 amino acids and resolutions between 0.

View Article and Find Full Text PDF

Memory for news stories was studied in 48 young and 48 old adults (20-40 and 60-80 years of age, respectively). Three stories selected from actual news programs were presented in print, audio, and TV formats for study. Young adults recalled a higher proportion of news content than old adults and performed better on source recognition tests.

View Article and Find Full Text PDF

An individual-differences approach was used to examine the component processes that predict episodic long-term memory performance. A total of 301 participants ages 20-90 received a 7-hr cognitive battery across 3 days. Key constructs hypothesized to affect long-term memory function were assessed, including multiple measures of working memory and perceptual speed.

View Article and Find Full Text PDF

The Stein paradigm was used to examine the circumstances under which verbal elaborations enhance memory in young and older adults. Subjects studied target adjectives that were embedded in one of three sentence contexts that varied in elaboration of the subject-adjective relationship: (1) nonelaborated base sentences; (2) base sentences with semantically consistent, but arbitrary verbal, elaborations; and (3) base sentences with explanatory verbal elaborations that clarified the significance of the subject-adjective relationship. The presence of the elaborations was varied at encoding and retrieval, and cued recall of the target adjectives was tested with incidental and intentional learning procedures.

View Article and Find Full Text PDF

We examined the effects of organization and working memory on young and older adults' scene memory. Subjects discriminated transformed pictures from unchanged study items in organized or unorganized scenes. Memory was tested independently for two types of scene transformations: (a) relocations (two objects rearranged and one moved) and (b) substitutions (one object replaced by another).

View Article and Find Full Text PDF