Publications by authors named "D Fridman"

Background: Antimicrobial-resistant (AMR) pathogens represent an ongoing global health burden. Colonization is often a prerequisite for infection, but the risk of infection after AMR colonization is not well understood. Using population-level health administrative data, we sought to investigate the risk of infection with the same AMR organism after detection of colonization.

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  • As global populations and wealth increase, the demand for food leads to greater water scarcity, highlighting the geopolitical importance of virtual water trade related to crops between countries.
  • This study examines the socio-ecological impacts of virtual water trade in Israel, a country that heavily relies on this trade, by analyzing the blue water consumption associated with up to 100 different crops.
  • Findings reveal that Israel's crop production significantly contributes to blue water consumption and identifies concerning trends in groundwater depletion, biodiversity loss, and regional impacts in places like India and the U.S.
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BACKGROUND Cesarean scar ectopic pregnancy is a rare type of ectopic pregnancy that can result in severe maternal morbidity and mortality. Medical, surgical, and minimally invasive therapies alone or in combination have been described in the literature, but the optimal treatment modality of cesarean scar ectopic pregnancies is unknown. Limited information exists on the course of cesarean scar ectopic pregnancy following treatment with cytotoxic agents.

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  • The study analyzed the risk factors and outcomes for patients with Gram-negative bloodstream infections (GN-BSI) who experience persistent bacteraemia, which is when bacteria remain in the bloodstream after initial treatment.
  • Out of 8807 hospitalized patients, 600 (6.8%) exhibited persistent bacteraemia, linked to factors like having a permanent catheter, antimicrobial resistance, ICU admission, and specific types of infections.
  • The research found that patients with persistent bacteraemia had significantly higher mortality rates within 30 days (17.2%) and 90 days (25.5%) compared to those without, suggesting the need for better risk assessment tools for these patients.
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Objectives: Data supporting routine infectious diseases (ID) consultation in gram-negative bloodstream infection (GN-BSI) are limited. We evaluated the association between ID consultation and mortality in patients with GN-BSI in a retrospective population-wide cohort study in Ontario using linked health administrative databases.

Methods: Hospitalized adult patients with GN-BSI between April 2017 and December 2021 were included.

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