Publications by authors named "D Frangoulidis"
Article Synopsis
- A Coxiella burnetii vaccination program targeted doelings on a German goat farm to reduce bacterial shedding, beginning with adult vaccinations in 2018 and continuing with two doses for doelings from 2019 to 2021.
- Monitoring involved vaginal swabs and bulk tank milk samples, revealing some ongoing shedding despite positive trends in antibody levels among vaccinated goats.
- Results showed that while double vaccination produced lasting antibody responses, it did not completely eliminate C. burnetii shedding, indicating the need for further research on the immune response.
Article Synopsis
- The Q-GAPS program started in 2017 in Germany and includes over 20 scientists studying a germ called Coxiella burnetii, which causes Q fever.
- They focus on understanding how this germ spreads between animals and humans and how to control outbreaks.
- Their work has led to new insights about vaccines, the germ's characteristics, and they created a website to share their findings and help public health officials manage Q fever better.
Q (query) fever is an infectious zoonotic disease caused by the Gram-negative bacterium Coxiella burnetii. Although the disease has been studied for decades, it still represents a threat due to sporadic outbreaks across farms in Europe. The absence of a central platform for typing data management is an important epidemiological gap that is relevant in the case of an outbreak.
View Article and Find Full Text PDFThe causative agent of Q fever, the bacterium (), has gained increasing interest due to outbreak events and reports about it being a potential risk factor for the development of lymphomas. In order to conduct large-scale studies for population monitoring and to investigate possible associations more closely, accurate and cost-effective high-throughput assays are highly desired. To address this need, nine proteins were expressed as recombinant antigens for multiplex serology.
View Article and Find Full Text PDFA Q fever outbreak on a dairy goat and cattle farm was investigated with regard to the One Health concept. Serum samples and vaginal swabs from goats with different reproductive statuses were collected. Cows, cats, and a dog were investigated with the same sample matrix.
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