Publications by authors named "D Fraisse"

Recently, the development of functional beverages has been enhanced to promote health and nutritional well-being. Thus, the fermentation of plant foods with lactic acid bacteria can enhance their antioxidant capacity and others like anti-inflammatory activity, which may depend on the variations in the total content and profile of (poly)phenols. The present study aimed to investigate the impact of fermentation with two strains of of several herbal infusions from thyme, rosemary, echinacea, and pomegranate peel on the (poly)phenolic composition and whether lacto-fermentation can contribute to enhance their in vitro antioxidant and anti-inflammatory effects on human colon myofibroblast CCD18-Co cells.

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Article Synopsis
  • Inflammation is a natural defense mechanism in our body, but it can become harmful if it lasts too long.
  • The study looks at how an extract from vine tea can reduce inflammation and prevent chronic diseases by targeting certain cells and proteins in the immune system.
  • The results show that this extract lowered harmful substances and changed the way immune cells behave, which suggests it could be helpful in managing long-term inflammation.
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Excess weight and obesity are the fifth leading cause of death globally, and sustained efforts from health professionals and researchers are required to mitigate this pandemic-scale problem. Polyphenols and flavonoids found in -a plant widely consumed as Rooibos tea-are increasingly being investigated for their positive effects on various health issues including inflammation. The aim of our study was to examine the effect of Rooibos extract on obesity and the associated low-grade chronic inflammatory state by testing antioxidant activity, cytokine secretions, macrophage polarization and the differentiation of human adipocytes through the development of adipospheroids.

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(1) Interest in the family has risen as some members have shown anti-inflammatory properties and interesting compounds. In this regard, we decided to investigate the antioxidant and anti-inflammatory properties of , a not yet extensively studied, in the context of osteoarthritis. (2) The Ethanol extract (LS-E) was used to test the production of reactive oxygen species (ROS) by leucocytes, the IL1β and PGE2 production by peripheral blood mononuclear cells (PBMCs), the production of EP4, and the activation of NFκB in THP-1, as well as the IL1β-activated normal human knee articular chondrocytes (NHAC-Kn) gene expression, grown in monolayers or maintained in alginate beads.

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Objectives: This study aimed to investigate the effect of the n-butanol fraction of the methanol leaf extract of (BFAC), growing wild in the arid zone of Tunisia, on induced obesity in male Wistar rats.

Methods: The total phenolic content and antioxidant capacity of the BFAC were estimated. The main phenolic composition of the BFAC was determined using the high-performance chromatography system coupled with a diode array detector technics.

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