Publications by authors named "D Fliss"
Multi-Institutional Comparison of Quality of Life Between Open Versus Endoscopic Skull Base Approaches.
Laryngoscope Investig Otolaryngol
February 2025
Objectives: The primary objective of this prospective review was to compare quality of life between patients undergoing endoscopic and open skull base approaches.
Study Type And Design: Prospective Review.
Methods: Five centers recruited consecutive patients treated surgically for skull base neoplasms between 2012 to 2018.
Article Synopsis
- A global collaborative study reviewed the management and outcomes of malignant skull base tumors, collecting data from 28 institutions involving 3,061 patients.
- The majority of surgeries utilized an open approach (55%), with endoscopic (36%) and combined techniques (9.6%) being less common, and the overall 5-year survival rates were 65% for overall survival (OS) and 71.7% for disease-specific survival (DSS).
- Factors such as older age, comorbidities, and the extent of tumor involvement were identified as independent predictors of survival, while adjuvant radiation therapy (RT) emerged as a protective factor in outcomes.
Background: This study compares early outcomes of osteofascial fibula free flap (OF-FFF) with donor-site primary closure and osteocutaneous (OC) FFF with donor-site skin grafting in segmental mandibular reconstruction.
Methods: A retrospective chart review of FFF mandibular reconstruction patients (2006-2022) divided into OF-FFF and OC-FFF groups. Clinical data, operative parameters, and early postoperative outcomes (≤ 90 days) were analyzed.
Acute facial nerve iatrogenic or traumatic injury warrants rapid management with the goal of reestablishing nerve continuity within 72 hours. However, reconstructive efforts should be performed up to 12 months from the time of injury since facial musculature may still be viable and thus facial tone and function may be salvaged. Data of all patients who underwent facial nerve repair following iatrogenic or traumatic injury were retrospectively collected and assessed.
View Article and Find Full Text PDFBackground: The presence of cervical lymph node (LN) metastasis at the initial presentation of papillary thyroid carcinoma (PTC) constitutes an independent risk factor for disease recurrence, increases the risk for mortality, and impacts overall outcome. The 2016 American Joint Committee on Cancer raised the age cutoff for PTC staging from 45 to 55 years for better prediction of overall survival. Age > 55 years is considered a significant risk factor for a more aggressive and advanced disease with worse outcomes.
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