Publications by authors named "D Flex"

Article Synopsis
  • The study examined the effectiveness of topical treatments for managing the rash caused by epidermal growth factor receptor inhibitors (EGFRIs) in cancer patients, which occurs in 60-85% of cases.
  • In a randomized trial, patients received either a combination ointment (chloramphenicol and prednisolone), chloramphenicol alone, or aqua cream to see how they influenced rash severity.
  • Results showed that the combination ointment significantly reduced the incidence of a specific type of significant rash compared to the aqua cream, suggesting it is a better prophylactic treatment.
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The original article [1] contained an error whereby all authors' names were mistakenly inverted. This error has now been corrected.

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Introduction: Advanced non-small cell lung cancer (NSCLC) is still a therapeutic challenge as the 5-year survival is under 30%. The optimal treatment regimen is still under debate.

Hypothesis: Neo adjuvant (NA) treatment given pre-pneumonectomy does not increase surgical complexity or peri-OP mortality while it has a potential to increase long term survival.

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Background: Trimodality therapy (chemoradiation followed by surgery) provides a benefit in progression-free survival but not overall survival. We sought to determine if a high dose of radiation could be delivered safely and provide a clinical benefit.

Methods: Consecutive patients with stage IIIA or IIIB non-small-cell lung cancer (NSCLC) treated with concurrent chemoradiotherapy followed by surgery were reviewed with IRB approval.

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Objectives: Nivolumab has recently received regulatory approval as a 2nd-line treatment of non-small cell lung cancer (NSCLC). The data regarding its effectiveness and safety in real life setting is lacking.

Materials And Methods: 260 consecutive patients with advanced NSCLC treated with nivolumab at five Israeli cancer centers between January 2015 and March 2016 were evaluated for overall survival (OS) and toxicity.

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