Publications by authors named "D Filipowicz"
Article Synopsis
- The study examines the potential of serum CD5L, a liver-derived protein, as an additional biomarker for assessing thyroid hormone (TH) status during pregnancy, where routine markers may change.
- Researchers developed a sensitive assay to measure CD5L levels and investigated factors that might influence its concentrations, finding that it remained stable and unaffected by circadian rhythms or liver disease.
- Results showed that CD5L positively correlated with free triiodothyronine (fT3) and trace elements like selenium and copper in pregnant women, suggesting its potential usefulness as a reliable TH status indicator, especially in pregnancy and thyroid-related conditions.
Assessment of Vitamin Concentrations in Patients with Hashimoto's Thyroiditis and Their Relationships with Thyroid Function, Biochemical Status, and Anthropometric Parameters-A Preliminary Study.
Nutrients
May 2024
Hashimoto's thyroiditis (HT) is the leading cause of hypothyroidism, affecting mainly the female population. Many patients with HT have metabolic disorders and nutritional deficiencies. The aim of this study was to evaluate vitamin D, A, E, B2, and B6 concentrations, thyroid function, metabolic profile, and anthropometric parameters of patients with Hashimoto's thyroiditis.
View Article and Find Full Text PDFPurpose: Differentiated thyroid cancer (DTC) presents a complex clinical challenge, especially in patients with distant metastases and resistance to standard treatments. This study aimed to investigate the influence of specific genes and their germline single nucleotide polymorphisms (SNPs) linked to both inflammatory processes and other neoplasms on the clinical and pathological characteristics of DTC, particularly their potential impact on radioiodine (RAI) treatment efficacy.
Methods: This retrospective analysis involved a cohort of 646 patients diagnosed with DTC after thyroidectomy.
The aim of this study was to compare the iron and calcium status in singleton and twin pregnancies and to assess whether there is an increased risk for iron and calcium deficiency in twin gestation. The study included 105 singleton and 9 twin pregnancies at or above 35 weeks of gestation. Information on prenatal supplementation with iron or calcium was acquired, and adverse perinatal outcomes were recorded.
View Article and Find Full Text PDFIntroduction: Iodine is a pivotal component of thyroid hormones, and its deficiency leads to negative pregnancy outcomes. Therefore, during gestation, additional iodine supplementation is recommended.
Objectives: By evaluating a group of women from western Poland, the study updated on iodine status during pregnancy and the effectiveness of iodine supplementation in relation to the maternal and neonatal thyroid function.