Publications by authors named "D Fernandez Reyes"

Aim: To explore nurse ability to recognize emotion and its association with clinical empathy.

Background: Empathy is elemental to nursing care and positively effects patient and nurse outcomes, yet self-reported clinical empathy has declined over the past decade. One hypothesized contributor to the ability of a nurse to be empathic is whether they can recognize emotion, a phenomenon thus far unstudied among nurses.

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  • The study focuses on evaluating the long-term outcomes and natural history of chronic subdural hematoma (cSDH) treatment using middle meningeal artery (MMA) embolization over a 12-month period.
  • A retrospective analysis was conducted involving 49 patients who underwent MMA embolization, detailing patient demographics and various clinical outcomes, including symptom resolution and recurrence rates.
  • Results indicated significant clinical improvement in patients within one month post-procedure, with many elderly patients (average age 73) experiencing previous trauma mainly due to falls.
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  • Pompe disease results from a deficiency in acid alpha-glucosidase, leading to muscle weakness, respiratory issues, and cardiomyopathy in infants; the only current treatment is enzyme replacement therapy (ERT).
  • A new approach using a Centyrin protein-conjugated short interfering RNA (siRNA) targets the transferrin receptor (CD71) and the GYS1 enzyme to inhibit glycogen synthesis, potentially restoring glycogen balance instead of just degrading it.
  • In tests on a Pompe mouse model, this novel siRNA conjugate effectively reduced GYS1 levels and glycogen accumulation, improving exercise performance, indicating its promise as a therapy for late-onset Pompe disease or in combination with ERT for infants.
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  • Infective endocarditis (IE) includes rare cases like Eustachian valve endocarditis (EVE), which can occur in patients without typical risk factors, as demonstrated in a 66-year-old male.
  • The patient showed various symptoms and complications, such as liver abscesses and spinal osteomyelitis, leading to the confirmation of EVE through transesophageal echocardiography (TEE) and blood cultures.
  • Successful treatment involved antimicrobial therapy, drainage of abscesses, and anticoagulation, highlighting the need for awareness of atypical endocarditis forms for timely diagnosis and management.
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Parkinson's disease (PD) is a growing public health challenge associated with the aging population. Current diagnostic methods rely on motor symptoms and invasive procedures, making early detection difficult. This study established a transferable artificial intelligence (AI) model, Quest2Dx, to analyze health questionnaires to enable low-cost and non-invasive PD diagnosis.

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